Peripheral neuropathic pain: signs, symptoms, mechanisms, and causes: are they linked?
نویسندگان
چکیده
منابع مشابه
Translation of symptoms and signs into mechanisms in neuropathic pain.
For centuries, clinicians have been taught to examine and classify patients on the basis of topographical lesion and the underlying pathology. In most clinical specialities, such an approach has been a key element in understanding the pathophysiology of diseases and has led to progress in terms of finding disease modifying or even disease curing therapies. Examples are multiple including bacter...
متن کاملNeuropathic Pain: Central vs. Peripheral Mechanisms.
PURPOSE OF REVIEW Our goal is to examine the processes-both central and peripheral-that underlie the development of peripherally-induced neuropathic pain (pNP) and to highlight recent evidence for mechanisms contributing to its maintenance. While many pNP conditions are initiated by damage to the peripheral nervous system (PNS), their persistence appears to rely on maladaptive processes within ...
متن کاملNeuropathic pain after brachial plexus avulsion - central and peripheral mechanisms
REVIEW The pain that commonly occurs after brachial plexus avulsion poses an additional burden on the quality of life of patients already impaired by motor, sensory and autonomic deficits. Evidence-based treatments for the pain associated with brachial plexus avulsion are scarce, thus frequently leaving the condition refractory to treatment with the standard methods used to manage neuropathic p...
متن کاملMechanisms of peripheral neuropathic pain: implications for musculoskeletal physiotherapy
Physiotherapy has long been part of the overall intervention for the attempted rehabilitation of patients with pain and disability following peripheral (and central) nerve damage. In musculoskeletal physiotherapy (a subspecialty), a movement-based assessment and treatment protocol has been devised that is guided by, among other things, therapists’ perceptions of patients’ responses to mechanica...
متن کاملMechanisms of neuropathic pain.
Neuropathic pain is de®ned as `pain initiated or caused by a primary lesion or dysfunction in the nervous system'. The spectrum of neuropathic pain covers a variety of disease states (Table 1) and presents in the clinic with a variety of symptoms. Neuropathic pain is often reported as having a lancinating or continuous burning character and is often associated with the appearance of abnormal se...
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ژورنال
عنوان ژورنال: British Journal of Anaesthesia
سال: 2015
ISSN: 0007-0912
DOI: 10.1093/bja/aeu323